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In utero gene therapy: The case against

✍ Scribed by Billings, Paul R.

Book ID: 109826883
Publisher: Nature Publishing Group
Year: 1999
Tongue: English
Weight: 61 KB
Volume: 5
Category: Article
ISSN: 1078-8956
DOI: 10.1038/6457

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## Abstract ## Background Brain‐directed prenatal gene therapy may benefit some lysosomal storage diseases that affect the central nervous system (CNS) before birth. Our previous study showed that intrauterine introduction of recombinant adenoviruses into cerebral ventricles results in efficient g