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In Thymic Selection, Peptide Diversity Gives and Takes Away

✍ Scribed by Michael J Bevan


Book ID
117722870
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
61 KB
Volume
7
Category
Article
ISSN
1074-7613

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## Abstract Fetal thymic organ cultures of N15‐transgenic RAG‐2^–/–^ H‐2^b^ mice on normal, β‐2 microglobulin (Ξ²2M)^–/–^ or transporter associated with antigen processing (TAP‐1)^–/–^ MHCI‐deficient backgrounds were used to examine differentiation of thymocytes bearing a TCR specific for a viral pe