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In situmRNA Hybridization Technique for Analysis of Human Telomerase RNA in Gastric Precancerous and Cancerous Lesions

โœ Scribed by Hiyama, Toru ;Yokozaki, Hiroshi ;Kitadai, Yasuhiko ;Tahara, Eiji ;Tahara, Hidetoshi ;Ide, Toshinori ;Haruma, Ken ;Yasui, Wataru ;Kajiyama, Goro ;Tahara, Eiichi


Book ID
108581537
Publisher
Wiley (Blackwell Publishing)
Year
1998
Tongue
English
Weight
359 KB
Volume
89
Category
Article
ISSN
0910-5050

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Upregulation of the ribonucleoprotein telomerase seems to be a prerequisite for immortality, a feature of malignant cells. Using a polymerase chain reaction (PCR)-based assay, it is possible to demonstrate telomerase activity (TA) in specimens of most human malignancies, whereas it is absent from mo