Demonstration of constant upregulation o
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Heine, Bernhard; Hummel, Michael; Demel, Gudrun; Stein, Harald
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Article
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1998
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John Wiley and Sons
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English
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Upregulation of the ribonucleoprotein telomerase seems to be a prerequisite for immortality, a feature of malignant cells. Using a polymerase chain reaction (PCR)-based assay, it is possible to demonstrate telomerase activity (TA) in specimens of most human malignancies, whereas it is absent from mo