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In situ proteolysis for protein crystallization and structure determination

✍ Scribed by Dong, Aiping; Xu, Xiaohui; Edwards, Aled M; Chang, Changsoo; Chruszcz, Maksymilian; Cuff, Marianne; Cymborowski, Marcin; Di Leo, Rosa; Egorova, Olga; Evdokimova, Elena


Book ID
109937698
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
121 KB
Volume
4
Category
Article
ISSN
1552-4450

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Microfluidics is a promising technology for the rapid identification of protein crystallization conditions. However, most of the existing systems utilize silicone elastomers as the chip material which, despite its many benefits, is highly permeable to water vapour. This limits the time available for