Sucrose gradient centrifugation of estrogen and progestin receptors in cytosol preparations revealed that the majority of human breast tumors contained two molecular forms sedimenting at either 8s or 4s. Few tumors exhibited profiles containing predominately the 8.9 form or the 4s form alone. Molecu
β¦ LIBER β¦
In situ production of sex steroids in human breast carcinoma
β Scribed by Takashi Suzuki; Yasuhiro Miki; Takuya Moriya; Jun-ichi Akahira; Hisashi Hirakawa; Noriaki Ohuchi; Hironobu Sasano
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 262 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0918-4287
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## Abstract The potential to metabolize endogenous and exogenous substances may influence breast cancer development and tumor growth. Therefore, the authors investigated the protein expression of Glutathione Sβtransferase (GST) isoforms and cytochrome P450 (CYP) known to be involved in the metaboli