In situ hybridization: perspectives of its clinical application in Hepatitis B and δ virus infections
✍ Scribed by Negro, Francesco ;Wells, Frances V. ;Rochee, Marlon ;Baroudy, Bahige M.
- Book ID
- 105656365
- Publisher
- Springer-Verlag
- Year
- 1988
- Weight
- 882 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0390-5748
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The presence of hepatitis B virus DNA and anti-b was examined in a longitudinal study of 24 patients known to be &infected during the course from acute to chronic hepatitis B virus infection. Fifteen patients (63%) were hepatitis B virus DNA positive in the first serum sample. Eleven of 14 patients,
Liver sections from 18 patients positive for hepatitis B surface antigen (HBsAg), and from 12 negative patients, were examined for the presence of hepatitis B virus (HBV) DNA using an in situ hybridization assay that would identify only those hepatocytes containing more than 10 to 15 HBV genome equi