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In situ hybridization of genes on metaphase chromosomes with non-radioactive probes at the EM level

✍ Scribed by A.F.M. Cremers; J.E. Landegent; M. van der Ploeg; A.J. Verkleij

Publisher: Elsevier Science
Year: 1987
Tongue: English
Weight: 210 KB
Volume: 21
Category: Article
ISSN: 0304-3991
DOI: 10.1016/0304-3991(87)90097-0

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## Abstract Fluorescence in situ hybridization for the __BCR__/__ABL__ rearrangement in 138 bone marrow specimens from 59 Philadelphia^+^ (Ph^+^) chronic myelogenous leukemia (CML) patients, 35 Ph^+^ acute lymphoblastic leukemia (ALL) patients, and 57 Ph^−^ ALL patients was used. Sixteen (27.1%) of