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In Situ Gene Therapy for Adenocarcinoma of the Prostate: A Phase I Clinical Trial

✍ Scribed by Herman, James R.; Adler, Howard L.; Aguilar-Cordova, Estuardo; Rojas-Martinez, Augusto; Woo, Savio; Timme, Terry L.; Wheeler, Thomas M.; Thompson, Timothy C.; Scardino, Peter T.

Book ID
125495329
Publisher
Mary Ann Liebert
Year
1999
Tongue
English
Weight
798 KB
Volume
10
Category
Article
ISSN
1043-0342

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## Abstract ## Objective: Preclinical evidence indicates that gene transfer to the dorsal root ganglion using replication‐defective herpes simplex virus (HSV)‐based vectors can reduce pain‐related behavior in animal models of pain. This clinical trial was carried out to assess the safety and explo