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In situ electrochemical and AFM study of thalidomide–DNA interaction

✍ Scribed by S.C.B. Oliveira; A.M. Chiorcea-Paquim; S.M. Ribeiro; A.T.P. Melo; M. Vivan; A.M. Oliveira-Brett

Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
634 KB
Volume
76
Category
Article
ISSN
1567-5394

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Electrochemical investigation of CuTMAP and its interaction with DNA at a Hg electrode is reported for the first time. The reduction of CuTMAP under our experimental conditions involves reduction of 2e of Cu 2/ and 2e of TMAP. Reaction of DNA with CuTMAP forms an electrochemically nonactive complex,