The putative prophylactic and therapeutic effect of interferon- (IFN-) on autoimmune inflammation of the peripheral nervous system was evaluated in experimental autoimmune neuritis (EAN), a well-known animal model of the human Guillain-Barre ´syndrome (GBS). We report that treatment of rats with 3
In situ demonstration of T cell activation and elimination in the peripheral nervous system during experimental autoimmune neuritis in the Lewis rat
✍ Scribed by U. K. Zettl; R. Gold; Klaus V. Toyka; Hans-Peter Hartung
- Publisher
- Springer-Verlag
- Year
- 1996
- Tongue
- English
- Weight
- 821 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0001-6322
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Natural killer (NK) cells are implicated in T cell‐mediated autoimmune diseases. Experimental autoimmune neuritis (EAN) is a CD4+ T cell‐mediated animal model of the Guillain‐Barré syndrome in human. The role of NK cells in the initiation and development of EAN remains unclear. In the p
T cell co-stimulation through the CD28 receptor on T cells is critical to the induction of experimental autoimmune encephalomyelitis (EAE). In this study, expression of the co-stimulatory ligands B7-1 (CD80) and B7-2 (CD86), as well as the receptors CD28 and CTLA-4, were quantitated in central nervo