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In situ cross-linkable hyaluronic acid hydrogels prevent post-operative abdominal adhesions in a rabbit model

โœ Scribed by Yoon Yeo; Christopher B. Highley; Evangelia Bellas; Taichi Ito; Robert Marini; Robert Langer; Daniel S. Kohane

Book ID
103825382
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
451 KB
Volume
27
Category
Article
ISSN
0142-9612

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The prevention of peritoneal adhesions b
The prevention of peritoneal adhesions by in situ cross-linking hydrogels of hyaluronic acid and cellulose derivatives
โœ Taichi Ito; Yoon Yeo; Christopher B. Highley; Evangelia Bellas; Carlos A. Benite ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 856 KB

Post-operative peritoneal adhesions can cause pelvic pain, infertility, and potentially lethal bowel obstruction. We have designed and synthesized injectable hydrogels that are formed by mixing hydrazide-modified hyaluronic acid (HA) with aldehyde-modified versions of cellulose derivatives such as c