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In situ assay for identifying inhibitors of bacterial transglycosylase

✍ Scribed by Arthur A Branstrom; Sunita Midha; Robert C Goldman


Book ID
117516568
Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
190 KB
Volume
191
Category
Article
ISSN
0378-1097

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Assay for Identification of Inhibitors f
✍ Arthur A. Branstrom; Sunita Midha; Clifford B. Longley; Kiho Han; Eugene R. Baiz πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 English βš– 64 KB

Bacterial peptidoglycan synthesis is a well-characterized system for targeting new antimicrobial drugs. Formation of the peptidoglycan precursors Lipid I and Lipid II is catalyzed by the gene products of mraY and murG, which are involved in the first and second steps of the lipid cycle reactions, re