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In situ analysis of manganese superoxide dismutase (MnSOD) in alveolar type II cells of hyperoxic rats

โœ Scribed by Renaud Vincent; Ye-Shih Ho; Ling-Yi Chang; Jan W. Slot; James D. Crapo


Book ID
113384807
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
137 KB
Volume
9
Category
Article
ISSN
0891-5849

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Distribution of mitochondrial manganese
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Enzymatic antioxidant defense systems, like superoxide dismutase (SOD), may protect neuronal and glial cells from reactive oxygen species (ROS) damage. Beside the cytosolic constitutive CuZn SOD, mitochondrial manganese SOD (Mn SOD) represents a ROS inducible enzyme which should allow the adaptation