In situ analysis of LKB1/STK11 mRNA expression in human normal tissues and tumours
β Scribed by Andrew Rowan; Michael Churchman; Rosemary Jefferey; Andrew Hanby; Richard Poulsom; Ian Tomlinson
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 385 KB
- Volume
- 192
- Category
- Article
- ISSN
- 0022-3417
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The presence of mRNA transcripts for cytokines in normal and neoplastic human breast tissue has been investigated. Using reverse transcriptase-linked polymerase chain reaction (RT-PCR), we have specifically screened for the following cytokines: interleukin (
## Abstract Aortic aneurisms are frequently asymptomatic but can induce dramatic complications. The diagnosis is only based on the aortic diameter and not on a structural and compositional basis. In this preliminary study, we propose infrared microspectroscopy to nondestructively probe normal and a
Gap junctional intercellular communication (GJIC) has been proposed as a cellular mechanism for tumour suppression and there is experimental evidence in support of this. If aberrant GJIC contributes to the formation of human breast tumours, one might expect that the connexins (gap junction proteins)
Malignant transformation of cells leads to the synthesis of large asparagine-linked oligosaccharides that exhibit a higher degree of beta 1,6 branching. In rodent and human tumor cell lines and certain human tumors, increased beta 1,6 branching of oligosaccharides has been shown to be associated wit