## Abstract Genetic engineering of metabolic pathways is a standard strategy to increase the production of metabolites of economic interest. However, such flux increases could very likely lead to undesirable changes in metabolite concentrations, producing deleterious perturbations on other cellular
✦ LIBER ✦
In silico strategy to rationally engineer metabolite production: a case study for threonine in Escherichia coli
✍ Scribed by P. De Atauri; J.C. Rodríguez-Prados; J. Maury; F. Ortega; J.C. Portais; C. Chassagnole; L. Acerenza; N.D. Lindley; M. Cascante
- Publisher
- Elsevier
- Year
- 2009
- Tongue
- English
- Weight
- 65 KB
- Volume
- 25
- Category
- Article
- ISSN
- 1871-6784
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
In silico strategy to rationally enginee
✍
Juan-Carlos Rodríguez-Prados; Pedro de Atauri; Jérôme Maury; Fernando Ortega; Je
📂
Article
📅
2009
🏛
John Wiley and Sons
🌐
English
⚖ 375 KB
Selectively Labeling the Heterologous Pr
✍
F.C.L. Almeida; G.C. Amorim; V.H. Moreau; V.O. Sousa; A.T. Creazola; T.A. Améric
📂
Article
📅
2001
🏛
Elsevier Science
🌐
English
⚖ 123 KB
Nuclear magnetic resonance is an important tool for high-resolution structural studies of proteins. It demands high protein concentration and high purity; however, the expression of proteins at high levels often leads to protein aggregation and the protein purification step can correspond to a high