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In silico prediction of aqueous solubility

✍ Scribed by Dearden, John C


Book ID
111674565
Publisher
Informa plc
Year
2006
Tongue
English
Weight
377 KB
Volume
1
Category
Article
ISSN
1746-0441

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In silico prediction of drug solubility:
✍ Kai LΓΌder; Lennart Lindfors; Jan Westergren; Sture Nordholm; Rasmus Persson; Mik πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 182 KB

## Abstract In view of the extreme importance of reliable computational prediction of aqueous drug solubility, we have established a Monte Carlo simulation procedure which appears, in principle, to yield reliable solubilities even for complex drug molecules. A theory based on judicious application