Targeting endothelin A receptor enhances
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Jeanett FischgrΓ€be; Martin GΓΆtte; Katharina Michels; Ludwig Kiesel; Pia WΓΌlfing
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Article
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2010
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John Wiley and Sons
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French
β 600 KB
Human epidermal growth factor receptor 2 (HER2) is frequently overexpressed in human breast cancers. It is known to drive tumor growth and progression and represents a prominent target in breast cancer therapy. The endothelin (ET) system, in particular ET-1 and its receptor ET A R, is of major relev