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In silico designing and optimization of anti-breast cancer antibody mimetic oligopeptide targeting HER-2 in women

✍ Scribed by Bashir A. Akhoon; Shishir K. Gupta; Vijeshwar Verma; Gagan Dhaliwal; Mugdha Srivastava; Shailendra K. Gupta; Raja Feroz Ahmad


Book ID
108181152
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
541 KB
Volume
28
Category
Article
ISSN
1093-3263

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Targeting endothelin A receptor enhances
✍ Jeanett FischgrΓ€be; Martin GΓΆtte; Katharina Michels; Ludwig Kiesel; Pia WΓΌlfing πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 French βš– 600 KB

Human epidermal growth factor receptor 2 (HER2) is frequently overexpressed in human breast cancers. It is known to drive tumor growth and progression and represents a prominent target in breast cancer therapy. The endothelin (ET) system, in particular ET-1 and its receptor ET A R, is of major relev