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In pursuit of the high-resolution structure of nicotinic acetylcholine receptors

✍ Scribed by Lin Chen


Book ID
110116996
Publisher
Cambridge University Press
Year
2010
Tongue
English
Weight
715 KB
Volume
588
Category
Article
ISSN
0022-3751

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## Abstract Nicotinic acetylcholine receptors (nAChRs), members of the Cys‐loop ligand‐gated ion channels (LGICs) superfamily, are involved in signal transduction upon binding of the neurotransmitter acetylcholine or exogenous ligands, such as nicotine. nAChRs are pentameric assemblies of homologou