In defence of twin studies: look to the phenotype
โ Scribed by Campbell, L.V.; Kelly, P.J.
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 19 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0742-3071
No coin nor oath required. For personal study only.
โฆ Synopsis
References
endothelial cell leukocyte adhesion plored in twin studies. Hawkes 1 accepts molecules in atherosclerosis. Thromthe high concordance in MZ twins for 1. Hawkes CH. Twin studies in diabetes bosis and Haemostasis 1994; 72: Type 1 diabetes in a study where insulin mellitus. Diabetic Med 1997; 14: 151-154. 347-352. treatment is the criterion for disease 8. Steiner M, Reinhardt KM, Krammer 2. Phillips DIW. Twin studies in medi-ascertainment. But from the same study B, Blann AD. Increased levels of cal research: can they tell us whether he defends a low concordance rate for soluble adhesion molecules in typediseases are genetically determined? Type 2 diabetes when Type 2 diabetes 2 (non-insulin dependent) diabetes Lancet 1993; 341: 1008-1009. was only diagnosed by medication use. mellitus are independent of glyca-3. Samaras K, Spector TD, Nguyen TV, The author notes that the study deliberemic control. Thrombosis and Hae-Baan K, Campbell LV, Kelly PJ. ately avoided testing the presumably nonmostasis 1994; 72: 979-984. Independent genetic factors deterdiabetic co-twin thereby avoiding overes-9. Krugluger W, Nell A, Solar P, mine the amount and distribution of timation of concordance. It is more prob-Matejka M, Boltz-Nitulescu G. fat in women after the menopause. able that concordance of the basic dia-Influence of sE-selectin and L-sel-J Clin Endocrinol Metab 1977; 82: betic disorder was underestimated. ectin on the regulation of cell 781-785. Moreover, while useful in Type 1 diabetes, migration during chronic peridon-4. Carey DPG, Nguyen T, Campbell treatment record ascertainment of the titis.
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