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In-cell generation of antibody single-chain Fv transcripts by targeted RNA trans-splicing

✍ Scribed by Jacob Schlesinger; Dina Arama; Hava Noy; Manar Dagash; Paula Belinky; Gideon Gross


Book ID
113716658
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
267 KB
Volume
282
Category
Article
ISSN
0022-1759

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## Abstract Inherent and acquired multidrug resistance (MDR) is characterized by a simultaneous resistance to diverse anticancer drugs and is a major impediment towards curative chemotherapy of cancer. Hence one important goal is to develop strategies aimed at specific targeting of major anticancer