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Improving the enantioselectivity of Candida rugosa lipase in the kinetic resolution of racemic methyl 2-(2,4-dichlorophenoxy)propionate

โœ Scribed by Antonio Cipiciani; Massimiliano Cittadini; Francesco Fringuelli


Book ID
104208659
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
468 KB
Volume
54
Category
Article
ISSN
0040-4020

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โœ Antonio Cipiciani; Francesco Fringuelli; Vittorio Mancini; Oriana Piermatti; Ann ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 305 KB

The enzymatic kinetic resolution of (-+)-4-acetoxy122]paracyclophane by Candida cylindracea lipase was investigated in water and in a two-phase aqueous organic system. The (+)-(R)-4-hydroxy-and (+)-(S)-4-acetoxyl2,2l-paracyclophanes were isolated in excellent yields and high enantiomeric excesses. T