Improving splitless injection with electronic pressure programming

✍ Scribed by Wylie, Philip L. ;Phillips, Richard J. ;Klein, Kenneth J. ;Thompson, Michael Q. ;Hermann, Bruce W.

• Book ID: 102894087
• Publisher: John Wiley and Sons
• Year: 1991
• Tongue: English
• Weight: 672 KB
• Volume: 14
• Category: Article
• ISSN: 0935-6304
• DOI: 10.1002/jhrc.1240141003

✦ Synopsis

Abstract

An experimental injection port has been designed for split or splitless sample introduction in capillary gas chromatography; the inlet uses electronic pressure control, in order that the column head pressure may be set from the GC keyboard, and the inlet may be used in the constant flow or constant pressure modes. Alternatively, the column head pressure may be programmed up or down during a GC run in a manner analogous to even temperature programming. Using electronic pressure control, a method was developed which used high column head pressures (high column flow rates) at the time of injection, followed by rapid reduction of the pressure to that required for optimum GC separation. In this way, high flow rates could be used at the time of splitless injection to reduce sample discrimination, while lower flow rates could be used for the separation. Using this method, up to 5 μl of a test sample could be injected in the splitless mode with no discrimination; in another experiment, 2.3 times as much sample was introduced into the column by using electronic pressure programming. Some GC peak broadening was observed in the first experiment.