Improving spatial resolution in SPECT with the combination of PSPMT based detector and iterative reconstruction algorithms

✍ Scribed by G.K. Loudos; K.S. Nikita; N.K. Uzunoglu; N.D. Giokaris; C.N. Papanicolas; S.C. Archimandritis; D. Varvarigou; D. Maintas

• Publisher: Elsevier Science
• Year: 2003
• Tongue: English
• Weight: 267 KB
• Volume: 27
• Category: Article
• ISSN: 0895-6111
• DOI: 10.1016/s0895-6111(02)00080-0

✦ Synopsis

This paper investigates the possibility of developing a SPECT system that combines the high spatial resolution of position sensitive photomultiplier tubes (PSPMTs) with the excellent performance of iterative reconstruction algorithms. A small field of view (FOV) camera based on a PSPMT and a pixelized scintillation crystal made of CsI(Tl) have been used for the acquisition of the projections. With the use of maximum likelihood expectation maximization (ML-EM) and ordered subsets expectation maximization (OSEM) slices of the object are obtained while three-dimensional (3D) reconstruction of the object is carried out using a modified marching cubes (MMC) algorithm. The spatial resolution of tomographic images obtained with the system was 2-3mm. The spatial resolution of a conventional system that uses filtered backprojection (FBP) for slices reconstruction was more than 9 mm.