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IMproving PArticipation of patients in Clinical Trials - rationale and design of IMPACT

โœ Scribed by Katrien Oude Rengerink; Brent C Opmeer; Sabine LM Logtenberg; Lotty Hooft; Kitty WM Bloemenkamp; Monique C Haak; Martijn A Oudijk; Marc E Spaanderman; Johannes J Duvekot; Christine Willekes; Maria G van Pampus; Martina M Porath; Jim van Eyck; Marko J Sikkema; Ben Willem J Mol

Book ID
115008575
Publisher
BioMed Central
Year
2010
Tongue
English
Weight
268 KB
Volume
10
Category
Article
ISSN
1471-2288

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IMPACT Recommendations for Improving the
IMPACT Recommendations for Improving the Design and Analysis of Clinical Trials in Moderate to Severe Traumatic Brain Injury
โœ Andrew I.R. Maas; Ewout W. Steyerberg; Anthony Marmarou; Gillian S. McHugh; Hest ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 83 KB

Clinical trials in traumatic brain injury (TBI) pose complex methodological challenges, largely related to the heterogeneity of the population. The International Mission on Prognosis and Clinical Trial Design in TBI study group has explored approaches for dealing with this heterogeneity with the aim