✦ LIBER ✦

Improving mass spectrometry for proteomics

Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 358 KB
Volume: 1
Category: Article
ISSN: 1748-0132
DOI: 10.1016/s1748-0132(06)70062-7

No coin nor oath required. For personal study only.

✦ Synopsis

TOOLS & TECHNIQUES UPDATE SPM probes are easy to handle

NanoWorld has introduced new pyrexnitride probes for a variety of scanning probe microscope (SPM) imaging techniques in air and liquid. The probes consist of Si 3 N 4 cantilevers and tips supported by a holder chip of pyrex glass. The multilever design provides either four rectangular or four triangular cantilevers, each having a reflective Cr/Au coating on the back. The low-stress Si 3 N 4 cantilevers and tips provide excellent hardness for wear resistance and longer lifetimes. The 4 µm-high tips have a typical radius of curvature of <15 nm. The holder chips provide easy handling and fit all wellknown commercial SPMs.

📜 SIMILAR VOLUMES

Improving mass measurement accuracy in m

Improving mass measurement accuracy in mass spectrometry based proteomics by combining open source tools for chromatographic alignment and internal calibration

✍ Magnus Palmblad; Yuri E.M. van der Burgt; Hans Dalebout; Rico J.E. Derks; Bart S 📂 Article 📅 2009 🏛 Elsevier 🌐 English ⚖ 256 KB

Accurate mass determination enhances peptide identification in mass spectrometry based proteomics. We here describe the combination of two previously published open source software tools to improve mass measurement accuracy in Fourier transform ion cyclotron resonance mass spectrometry (FTICRMS). Th

Mass spectrometry and proteomics

✍ Steven P Gygi; Ruedi Aebersold 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 249 KB

Proteomics is the systematic analysis of the proteins expressed by a cell or tissue, and mass spectrometry is its essential analytical tool. In the past two years, incremental advances in standard proteome technology have increased the speed of protein identification with higher levels of automation

Perspectives for mass spectrometry and f

Perspectives for mass spectrometry and functional proteomics

✍ Jasminka Godovac-Zimmermann; Larry R. Brown 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 979 KB

Microfluidic chips for mass spectrometry

Microfluidic chips for mass spectrometry-based proteomics

✍ Jeonghoon Lee; Steven A. Soper; Kermit K. Murray 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 736 KB

## Abstract Microfluidic devices coupled to mass spectrometers have emerged as excellent tools for solving the complex analytical challenges associated with the field of proteomics. Current proteome identification procedures are accomplished through a series of steps that require many hours of labo

Quantitative proteomics using mass spect

Quantitative proteomics using mass spectrometry

✍ Salvatore Sechi; Yoshiya Oda 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 157 KB

The use of stable isotopes as internal standards in mass spectrometry has opened a new era for quantitative proteomics. Depending on the point at which the label is introduced, most procedures can be classified as in vivo labeling, in vitro pre-digestion labeling or in vitro post-digestion labeling.

Proteomic tools for quantitation by mass

Proteomic tools for quantitation by mass spectrometry

✍ Jennie Lill 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 157 KB

## Abstract | I. | Introduction | 182 | | II. | Relative Quantitation | 184 | | | A. 2‐D Gel Electrophoresis | 184 | | | B. Metabolic Isotopic Labeling | 185 | | | 1. ^15^N | 185 | | | 2. ^13^C Enrichment and Depletion | 185 | | | 3. Select Isotopic Amino Acid Incorporation