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Improving live attenuated bacterial carriers for vaccination and therapy

✍ Scribed by Holger Loessner; Anne Endmann; Sara Leschner; Heike Bauer; Andrea Zelmer; Susanne zur Lage; Kathrin Westphal; Siegfried Weiss

Book ID
116558297
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
202 KB
Volume
298
Category
Article
ISSN
1438-4221

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## Abstract Systemic administration of cytokines has shown therapeutic benefits in cancer patients; however, serious adverse effects associated with direct protein administration prevent the wide use of this approach. We have assessed the capacity of live attenuated __Salmonella__ to act as a vecto