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Improving lipoplex-mediated gene transfer into C6 glioma cells and primary neurons

✍ Scribed by M.Teresa Girão da Cruz; Sérgio Simões; Maria C. Pedroso de Lima


Book ID
116458190
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
881 KB
Volume
187
Category
Article
ISSN
0014-4886

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## Abstract In brain, levels of adenosine increase up to 100‐fold during cerebral ischemia. Based on in vitro studies, both astrocytes and neurons contribute to this adenosine release. Neurons release adenosine per se whereas astrocytes release adenine nucleotides that are metabolized to adenosine