## Abstract ## Background The use of retroviral vectors has shown an actual clinical benefit in a few inherited diseases. However, the occurrence of cases of leukemia after the XβSCID gene therapy trial raised concerns about the safety of insertional mutagenesis inherent to the biology of the retr
β¦ LIBER β¦
Improvements in an in-vitro assay for excitotoxicity by measurement of early gene (c-fosmRNA) levels
β Scribed by Annamarie Rogers; Gabriele Schmuck; Gabriele Scholz; Roger Griffiths; Clive Meredith; Arne Schousboe; Giuseppe Campiani; D. Clive Williams
- Publisher
- Springer-Verlag
- Year
- 2004
- Tongue
- English
- Weight
- 448 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0340-5761
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## Abstract Quantitation assays of HIVβ1 RNA used currently were designed and optimized for subtype B viruses. However, infection with nonβB HIV viruses has become more common worldwide. Unfortunately, little information is available regarding the suitability of these assays for measurement of vira