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Improvement of the T-cell response to a non-immunogenic peptide by its tandem association with a highly efficient T-helper peptide

✍ Scribed by Franck Rouaix; Hélène Gras-Masse; Christine Mazingue; Pierre-Richard Ridel; Eric Diesis; Monique Marguerite; Jérôme Estaquier; André Capron; André Tartar; Claude Auriault


Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
561 KB
Volume
28
Category
Article
ISSN
0162-3109

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## Abstract The Ii‐Key fragment from the MHC class II‐associated invariant chain (or Ii protein) has been shown to facilitate direct charging of MHC class II epitopes to the peptide binding groove. The purpose of the present study was to test the potential of a series of Ii‐Key/HER‐2__/neu__(776–79