✦ LIBER ✦

Improvement of the reproducibility of ion-pair HPLC of 99mTc(Sn)EHDP complexes and the influence of the Sn(II) concentration on the composition of the reaction mixture

✍ Scribed by R.J.A. Nieuwland; H.A. Das; C.L. de Ligny

Publisher: Elsevier Science
Year: 1989
Weight: 370 KB
Volume: 40
Category: Article
ISSN: 0883-2889
DOI: 10.1016/0883-2889(89)90191-3

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The separation of 99mTc(Sn) EHDP complex

The separation of 99mTc(Sn) EHDP complexes by HPLC and GPC

✍ G.J. de Groot; H.A. Das; C.L. de Ligny 📂 Article 📅 1986 🏛 Elsevier Science ⚖ 449 KB

For the characterization of the multi-component bone-scan agent 99mTc(Sn)EHDP we have analysed the complex mixture with reversed phase ion pair chromatography (IPC) and soft gel permeation chromatography (GPC). With IPC five major complexes were found within a separation-time of 40 min. To avoid dec

The effect of DMSO treatment on the comp

The effect of DMSO treatment on the composition of 99mTc(Sn)EHDP

✍ G.J. De Groot; H.A. Das; C.L. De Ligny 📂 Article 📅 1986 🏛 Elsevier Science ⚖ 315 KB

To find an explanation for the reported positive effect of a dimethyl sulfoxide (DMSO) treatment on the performance of the bone scan agent technetium-(tin)-ethane-1-hydroxy-1, 1-diphosphonate, we compared the composition of the agent, prepared with and without treatment with DMSO by using high perfo

The influence of experimental conditions

The influence of experimental conditions on the formation of various 99mTc(Sn)EHDP complexes

✍ J.A.G.M. van den Brand; H.A. Das; B.G. Dekker; C.L. de Ligny 📂 Article 📅 1982 🏛 Elsevier Science ⚖ 391 KB

Gel chromatographic analysis of the bone

Gel chromatographic analysis of the bone seeking radiopharmaceutical 99mTc(Sn)-EHDP: The influence of pH and EHDP-concentration on the size of its constituents

✍ Y.M. Huigen; W.J. Gelsema; C.L. de Ligny 📂 Article 📅 1987 🏛 Elsevier Science ⚖ 333 KB

Anion exchange chromatography of 99mTc(S

Anion exchange chromatography of 99mTc(Sn)EHDP complexes: Determination of the charge of the components and influence of pH and ligand concentration

✍ Y.M. Huigen; M. Diender; W.J. Gelsema; C.L. De Ligny 📂 Article 📅 1991 🏛 Elsevier Science ⚖ 563 KB

The components of a 99mTc(Sn)-EHDP complex mixture were separated by means of normal pressure and high-pressure anion exchange chromatography, on DEAE-Trisacryl and Aminex, respectively. Precautions were taken to prevent the dissociation of the complexes during chromatography. The charges of the com

The influence of the method of preparati

The influence of the method of preparation of the bone scanning agent 99mTc(Sn)EHDP on its tissue distribution in the rat

✍ J.A.G.M. Van den Brand; H.A. Das; B.G. Dekker; C.L. De Ligny; C.J.A. Van den Ham 📂 Article 📅 1982 🏛 Elsevier Science ⚖ 983 KB