Improvement of systemic absorption of insulin through eyes with absorption enhancers
β Scribed by George C. Y. Chiou; Ching Yao Chuang
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 386 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A series of new glycosides with extended alkyl side-chains (C(13-16)) linked to maltose or sucrose were synthesized and tested for their efficacy in enhancing nasal insulin absorption in anesthetized rats. The new reagents were compared to previously tested alkylglycosides with shorter alkyl side ch
## Abstract The purpose of this work was to investigate chitosanβ__N__βacetylβLβcysteine (chitosanβNAC) nanoparticles as a potential carrier system for the nasal delivery of insulin. For the study, we used insulinβloaded chitosanβNAC nanoparticles (140β210 nm in diameter) prepared by __in situ__ ge
The absorption-enhancing effects of polyamidoamine (PAMAM) dendrimers with various generations (G0-G3) and concentrations [0.1%-1.0% (w/v)] on the pulmonary absorption of peptide and protein drugs were studied in rats. Insulin and calcitonin were chosen as models of peptide and protein drugs, and th
Effects of chitosan oligomers on pulmonary absorption of interferon-a (IFN) were examined by means of an in vivo pulmonary absorption experiment. Chitosan oligomers used in this study were chitosan dimer, tetramer, hexamer, and water-soluble (WS) chitosan. A significant increase in serum IFN concent