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Improvement of neuronal visual responses in the superior colliculus in Prph2Rd2/Rd2 mice following gene therapy

✍ Scribed by F.C Schlichtenbrede; A.J Smith; J.W.B Bainbridge; A.J Thrasher; T.E Salt; R.R Ali


Book ID
116735125
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
467 KB
Volume
25
Category
Article
ISSN
1044-7431

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## Abstract ## Background __Prph2__^Rd2/Rd2^ mice have a retinal degeneration due to a null mutation for the __Prph2__ gene which encodes a photoreceptor‐specific glycoprotein, peripherin2, essential for outer‐segment formation. We have previously shown improvement of photoreceptor function at a s