Improvement of macromolecular clearance via lymph flow in hamster gingiva by low-power carbon dioxide laser-irradiation
✍ Scribed by Akira Shimotoyodome; Miyuki Okajima; Hisataka Kobayashi; Ichiro Tokimitsu; Akira Fujimura
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 605 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0196-8092
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Background and Objective
Although therapeutic effects of low‐power laser‐irradiation on periodontal disease have been reported, little is known about the biological effects of laser‐irradiation in the gingiva. Recently we reported that topical warming stimulated macromolecular clearance via lymph flow in hamster gingiva. This study was conducted to investigate whether low‐power laser‐irradiation affects macromolecular clearance via the lymph flow in the gingiva.
Study Design/Materials and Methods
We injected ^14^C‐methylated albumin into the mandibular gingiva of anesthetized hamsters followed by topical carbon dioxide (CO~2~) laser‐irradiation (30 seconds, 0.5–1.5 W). We measured the clearance of radiolabeled albumin from the gingiva and its drainage into submandibular lymph nodes during 10 minutes.
Results
The clearance of the radiolabeled albumin from the gingiva and the influx into the submandibular lymph nodes were increased by CO~2~ laser‐irradiation.
Conclusion
Low‐power CO~2~ laser‐irradiation improves macromolecular clearance via the lymph flow in hamster gingiva. Lasers Surg. Med. 29:442–447, 2001. © 2001 Wiley‐Liss, Inc.