Improvement of lung function in patients with systemic sclerosis after 6
β Scribed by Predrag Ostojic; Nemanja Damjanov
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 73 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0770-3198
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π SIMILAR VOLUMES
## Abstract ## Objective Increased endothelin activity may play a role in the pathogenesis of vascular injury, a primary feature of systemic sclerosis (SSc; scleroderma). Our goal was to test the hypothesis that treatment with the oral endothelin receptor antagonist bosentan might improve vascular
D-penicillamine has been used to treat systemic sclerosis (scleroderma) for nearly two decades. Improvement in cutaneous fibrosis in patients treated with this drug has been documented in a number of uncontrolled studies (1). The effect of D-penicillamine on established visceral involvement due to s