Improvement in treatment results of gastric cancer with surgery and chemotherapy: Experience of 9,700 cases in the cancer institute hospital, Tokyo

✍ Scribed by Toshifusa Nakajima; Mitsumasa Nishi; Tamaki Kajitani

• Book ID: 104594107
• Publisher: John Wiley and Sons
• Year: 1991
• Tongue: English
• Weight: 615 KB
• Volume: 7
• Category: Article
• ISSN: 8756-0437
• DOI: 10.1002/ssu.2980070608

✦ Synopsis

Treatment results of 9,741 cases of gastric cancer treated at the Cancer Institute Hospital, Tokyo during the past 42 years were retrospectively analyzed. Resectability was 89.6% (94.1% for 1960-1988) and operative mortality was 1. 9% (1.5% for 1960-1988). Five-year survival rate was 48. 5% (54.9% for 1960-1988) for all cases, 68.8% (73.1% for 1960-1988) for patients with curative surgery, and 4.7% (4.9% for 1960-1988) for those with noncurative surgery. Curative rate was improved twofold among patients with curative gastrectomy. Postoperative adjuvant chemotherapy had a marginal benefit for stage I1 and 111 disease. Improvement could be attributed mainly to the relative increase in early gastric cancer, and partly to the extended surgeries for stage 111 and IV cases, such as systemic lymphadenectomy and combined resection of involved adjacent organs. Multimodality therapy is expected to control the relapse of peritoneal dissemination (14.2%) and hematogenous metastasis (8.9Y0).