Improvement (5-fold) of enantioselectivity for lipase-catalyzed esterification of a bulky substrate at 57°c in organic solvent

✍ Scribed by Yoshitaka Yasufuku; Shinichi Ueji

• Publisher: Springer-Verlag
• Year: 1996
• Tongue: English
• Weight: 257 KB
• Volume: 10
• Category: Article
• ISSN: 0951-208X
• DOI: 10.1007/bf00157374

✦ Synopsis

A reaction temperature at S7OC produced an improvement of lipase's enantioselectivity for an esterification of a bulky substrate, such as 2-(2-methyl-or 4-trrr-butyl-phenoxy)propionic acid. in organic solvent with a suitable amount of water added. although the poor enantioselectivity was observed for its bulky substrate under ordinary reaction conditions.