## Abstract Insulinβlike growth factor binding proteinβ1 (IGFBPβ1) is synthesized in the liver and regulates the mitogenic effects of the insulinβlike growth factors (IGFs). The evidence that IGFBPβ1 plays a role in hepatocarcinogenesis, however, is equivocal. We have, therefore, investigated the d
Improved Wool Production in Transgenic Sheep Expressing Insulin-like Growth Factor 1
β Scribed by Damak, Sami ;Su, Hung-yi ;Jay, Nigel P. ;Bullock, David W.
- Book ID
- 109901846
- Publisher
- Nature Publishing Group
- Year
- 1996
- Tongue
- English
- Weight
- 540 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1087-0156
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Multiple factors contribute to the growth retardation which is a characteristic feature of uncontrolled diabetes. In this report we have examined the effects of streptozotocin-induced (STZ) diabetes on expression of insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-
## Abstract To assess the roles of developmental factors in the regulation of sheep IGFBP production at the cellular level, we characterized and compared the IGFBPs released by fetal, postnatal, and maternal sheep skin fibroblasts in culture with those in fetal, postnatal, and maternal sheep plasma