## Abstract Ovarian cancer is the fourth most common cause of cancer deaths among females in the western world after cancer of the breast, colon and lung. The inability to control the disease within the peritoneal cavity is the major cause of treatment failure in patients with ovarian cancer. The m
Improved targeting of the αvβ3integrin by multimerisation of RGD peptides
✍ Scribed by Ingrid Dijkgraaf; John A. W. Kruijtzer; Shuang Liu; Annemieke C. Soede; Wim J. G. Oyen; Frans H. M. Corstens; Rob M. J. Liskamp; Otto C. Boerman
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 179 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0340-6997
No coin nor oath required. For personal study only.
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## Abstract ## Purpose: To investigate the targeting activity of the peptide (named P1c) derived from connective tissue growth factor (CTGF) to αvβ3‐rich tumor cells. ## Materials and Methods: P1c was synthesized and conjugated with ultrasuperparamagnetic iron oxide particles (USPIOs) coated wit