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Improved Synthesis of Three Brominated Analogues of the Potent Environmental Mutagen 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX)

✍ Scribed by Maia Lloveras; Isabel Ramos; Elies Molins; Angel Messeguer


Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
125 KB
Volume
56
Category
Article
ISSN
0040-4020

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✦ Synopsis


AbstractÐThe synthesis of three brominated analogues of the environmental mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)furanone (MX), namely, 3-chloro-4-(bromochloromethyl)-5-hydroxy-2(5H)-furanone (BMX-1), 3-chloro-4-(dibromomethyl)-5-hydroxy-2(5H)-furanone (BMX-2) and 3-bromo-4-(dibromomethyl)-5-hydroxy-2(5H)


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ChemInform Abstract: Improved Synthesis
✍ Maia Lloveras; Isabel Ramos; Elies Molins; Angel Messeguer πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons βš– 32 KB πŸ‘ 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

Developmental toxicity evaluation of 3-c
✍ Hannele Huuskonen; Raili VenΓ€lΓ€inen; Hannu Komulainen πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 101 KB πŸ‘ 1 views

## Abstract 3‐Chloro‐4‐(dichloromethyl)‐5‐hydroxy‐2(5__H__)‐furanone (MX) is a genotoxic chlorination by‐product in drinking water. There is some evidence that it has developmental toxic effects in vitro but its potential to cause developmental effects in vivo is not known. The developmental effect