Improved Synthesis of the FR900482 and Mitomycin Benzazocine Ring Core via Mitsunobu Cyclization.
β Scribed by Pascal Ducept; Daniel A. Gubler; Robert M. Williams
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 18 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The nucleus of the carbacephem antibiotic loracarbef was synthesized in a highly efficient and enantioselective fashion from 2S,3S-2-amino-3-hydroxy-6-heptenoic acid (AHHA), which was derived from enzyme-catalyzed condensation of glycine and 4-pentenaldehyde. The bicyclic framework of this compound
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract The stereoselective rearrangement of tetrahydrofuran or tetrahydropyran rings having a phenylsulfanyl group in an __exo__ position, __via__ the intermediate thiiranium ions, is reported. The 5β or 6β__exo__βtet cyclization of hydroxy sulfides gave the kinetic products while the 6β__endo