๐”– Bobbio Scriptorium
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Improved synthesis and pharmacologic activity of the enantiomers of a new benzofurane type antiarrhythmic compound

โœ Scribed by Gerhard Ecker; Wilhelm Fleischhacker; Thomas Helml; Dr. Christian R. Noe; Sonja Scasny; Rosa Lemmens-Gruber; Christian Studenik; Hesham Marei; Peter Heistracher


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
724 KB
Volume
6
Category
Article
ISSN
0899-0042

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๐Ÿ“œ SIMILAR VOLUMES


Chiral synthesis and pharmacological eva
โœ Maria Novella Romanelli; Alessandro Bartolini; Carlo Bertucci; Silvia Dei; Carla ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 527 KB

The enantiomers of 3-a-tropyl 2-(phenylthio) butyrate (SMT2, 1 ) were prepared by chiral synthesis and tested for analgesic, cognition-enhancing, and ACh-releasing properties. They show enantioselectivity in some of the tests, the eutomer being related in configuration to R-( +)-hyoscyamine.