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Improved structural characterization of chromosomal breakpoints using high resolution custom array-CGH

✍ Scribed by A Lindstrand; J Schoumans; P Gustavsson; N Hanemaaijer; H Malmgren; E Blennow


Book ID
110888951
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
865 KB
Volume
77
Category
Article
ISSN
0009-9163

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## Abstract Understanding the genes and genetic pathways targeted by recurrent chromosomal imbalances in malignancy, along with the molecular mechanisms that generate the imbalances, are important problems in cancer biology. In this report, we demonstrate that oligonucleotide array CGH (oaCGH) anal