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Improved stability and selectivity of lytic peptides through self-assembly

✍ Scribed by Zhigang Tu; Jumin Hao; Riddhi Kharidia; Xiao G. Meng; Jun F. Liang

Book ID
116295304
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
545 KB
Volume
361
Category
Article
ISSN
0006-291X

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πŸ“œ SIMILAR VOLUMES

Lytic peptides with improved stability a
Lytic peptides with improved stability and selectivity designed for cancer treatment
✍ Long Chen; Zhigang Tu; Natalya Voloshchuk; Jun F. Liang πŸ“‚ Article πŸ“… 2012 πŸ› John Wiley and Sons 🌐 English βš– 524 KB

Lytic peptides are a group of membrane-acting peptides, which have excellent activity to drug-resistant cells. In this study, the stability and tumor selectivity of newly designed pH-activated lytic peptides were studied. We found that despite varied secondary structures, pH-induced structure change