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Improved solid-state NMR quantifications of active principles in pharmaceutical formulations

✍ Scribed by Stéphanie Sanchez; Fabio Ziarelli; Stéphane Viel; Corinne Delaurent; Stefano Caldarelli


Book ID
108189527
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
327 KB
Volume
47
Category
Article
ISSN
0731-7085

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Crystalline lactose was subjected to various forms of pharmaceutical processing including compaction, lyophilization, spray drying, and cryogrinding. (13)C cross polarization and magic-angle spinning (CPMAS) NMR spectra were acquired for bulk crystalline lactose as well as the processed samples. Sat