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Improved resolution of (±)-trans-2'-hydroxy-5,9-dimethyl-6,7-benzomorphans

✍ Scribed by Joseph R. Wetzel; John D. Grego; John P. Mallamo


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
331 KB
Volume
4
Category
Article
ISSN
0899-0042

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## Abstract (+)‐__N__‐[^11^C]‐Benzyl‐__N__‐normetazocine (1__S__,5__S__,9__S__‐(+)‐__cis__‐2‐[^11^C]‐benzyl‐2′‐hydroxy‐5,9‐dimethyl‐6,7‐benzomorphan), a potent and selective ligand for the σ receptor, was prepared by N‐benzylation of (+)‐__cis__‐__N__‐normetazocine with [α‐^11^C]‐benzyl iodide in e