✦ LIBER ✦

Improved renal transplantation in the rat with a nonsplinted ureteroureterostomy

✍ Scribed by Yan Li Gu; Uta Dahmen; Olaf Dirsch; Christoph Erich Broelsch

Publisher: John Wiley and Sons
Year: 2002
Tongue: English
Weight: 182 KB
Volume: 22
Category: Article
ISSN: 0738-1085
DOI: 10.1002/micr.22510

No coin nor oath required. For personal study only.

✦ Synopsis

Orthotopic renal transplantation in the rat is a widely used model in immunology and transplantation-related research. Although numerous modifications of the surgical technique of ureteric reconstruction were evaluated, ureter complications following this reconstruction still occurred frequently. Instead of dividing the ureter in the middle between kidney and bladder (method 1), the anastomosis was performed close to the renal pelvis after cutting the ureter obliquely (method 2), which enlarged the diameter of the ureteral anastomosis 2-fold. The incidence of stenosis of ureteric anastomosis was 12.5% (3/24) using method 1, whereas this complication was avoided completely (0/45) using method 2. Furthermore, the risk of injury to the ureter was reduced, as isolation of the ureter was limited. These modifications improved the last delicate step in the procedure of rat kidney transplantation.

📜 SIMILAR VOLUMES

A more versatile and reliable method for

A more versatile and reliable method for renal transplantation in the rat

✍ Dennis Blom; Mark S. Orloff 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 265 KB 👁 2 views

This study describes the authors' experience with a new method of orthotopic renal transplantation in the rat. This technique combines previously described modifications with the use of the donor inferior vena cava as a conduit to perform an end-to-side venous anastomosis. Survival was 87% and 80% a

Improvement of renal function after the

Improvement of renal function after the switch from a calcineurin inhibitor to everolimus in liver transplant recipients with chronic renal dysfunction

✍ Javier F. Castroagudín; Esther Molina; Rafael Romero; Esteban Otero; Santiago To 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 141 KB 👁 1 views

Chronic renal dysfunction is a frequent and severe complication in solid-organ transplant recipients. Calcineurin inhibitors (CNIs) are the main pathogenic factors of renal dysfunction. Switching from CNIs to nonnephrotoxic drugs, such as mammalian target of rapamycin inhibitors (everolimus and siro

Gene therapy with adenovirus-delivered i

Gene therapy with adenovirus-delivered indoleamine 2,3-dioxygenase improves renal function and morphology following allogeneic kidney transplantation in rat

✍ Diana Vavrincova-Yaghi; Leo E. Deelman; Harry van Goor; Marc Seelen; Ido P. Kema 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 285 KB

## Abstract ## Background Indoleamine 2,3‐dioxygenase (IDO), the rate‐limiting enzyme in the tryptophan catabolism, has recently emerged as an important immunosuppressive enzyme involved in the regulation of both physiologic (maternal tolerance), as well as pathologic (neoplasia, autoimmune diseas

Auxiliary liver transplantation with por

Auxiliary liver transplantation with portal arterialization in the rat: description of a new model

✍ Javier Aguirrezabalaga; Francisco Arnal; Milagros Marini; Alberto Centeno; Carlo 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 138 KB

## Abstract In recent years, portal arterialization has been used in liver transplantation to increase the portal flow, as a solution for singular technical problems. We have developed a new auxiliary liver transplantation model in the rat with portal arterialization, so the native hepatic hilium r

Reflex sympathetic dystrophy syndrome of

Reflex sympathetic dystrophy syndrome of the lower limbs in renal transplant patients treated with cyclosporin A

✍ Jose Muñoz-Gomez; Antonio Collado; Jordi Gratacós; Joaquin Llena; J. M. Campisto 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 698 KB

Multifocal aggressive lymphoma of the ga

Multifocal aggressive lymphoma of the gastrointestinal tract in a renal transplant patient treated with cyclosporin a and prednisone

✍ Carlos J. Castro; Paul Klimo; Anne Worth 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 353 KB 👁 2 views

This is a case report of an aggressive multifocal non-Hodgkin's lymphoma in a cadaver kidney recipient arising in the early phase of her immunosuppressive maintenance therapy program with cyclosporin A and prednisone.