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Improved quantification of HIV-1-infected CD4+ T cells using an optimised method of intracellular HIV-1 gag p24 antigen detection

✍ Scribed by Yang, Hongbing; Yorke, Elisabeth; Hancock, Gemma; Clutton, Genevieve; Sande, Nellia; Angus, Brian; Smyth, Redmond; Mak, Johnson; Dorrell, Lucy


Book ID
122868424
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
419 KB
Volume
391
Category
Article
ISSN
0022-1759

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For some membrane-associated antigens, the number of molecules expressed per cell carries information about the cell's differentiation and activation state. Quantitating antigen expression by flow cytometry has immediate application in monitoring CD38 expression on CD8 Ψ‰ T cells in human immunodefic