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Improved production of A40926 byNonomuraeasp. through deletion of a pathway-specific acetyltransferase

✍ Scribed by Margherita Sosio; Augusto Canavesi; Sofia Stinchi; Stefano Donadio

Publisher
Springer
Year
2010
Tongue
English
Weight
190 KB
Volume
87
Category
Article
ISSN
1432-0614

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## Abstract In this report, small‐scale culture and bioreactor experiments were used to compare and improve the heterologous production of the antibiotic erythromycin A across a series of engineered prototype __Escherichia coli__ strains. The original strain, termed BAP1(pBPJW130, pBPJW144, pHZT1,