Improved Prediction of Protein Binding Sites from Sequences Using Genetic Algorithm
β Scribed by Xiuquan Du; Jiaxing Cheng; Jie Song
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 704 KB
- Volume
- 28
- Category
- Article
- ISSN
- 1573-4943
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
We describe a rapid and sensitive method to isolate sets of high-affinity binding sites for sequence-specific DNA binding proteins. The DNA binding domain of the protein is expressed in Escherichia coli as a fusion with glutathione S-transferase (GST). Binding reactions are set up with total soluble
## Abstract The ability to predict protein folding rates constitutes an important step in understanding the overall folding mechanisms. Although many of the prediction methods are structure based, successful predictions can also be obtained from the sequence. We developed a novel method called pred