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Improved pH-independent dissolution and oral absorption of valsartan via the preparation of solid dispersion

✍ Scribed by Young Joon Park; Hyoung-Kyu Lee; Young Bin Im; Wonjae Lee; Hyo-Kyung Han


Book ID
107642308
Publisher
Springer
Year
2010
Tongue
English
Weight
379 KB
Volume
33
Category
Article
ISSN
0253-6269

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Improvement of dissolution and oral abso
✍ Ikuo Kushida; Masaki Ichikawa; Naoki Asakawa πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 215 KB

Several formulation approaches were attempted to improve the dissolution and the oral absorption of ER-34122, which is a novel dual 5-lipoxygenase/ cyclooxygenase inhibitor with potent anti-inΒ―ammatory activity. The solid dispersion of ER-34122 with hydroxypropylmethylcellulose (TC-5RW), which is an